diff --git a/.changeset/calm-toes-melt.md b/.changeset/calm-toes-melt.md
new file mode 100644
index 0000000000..b8a7b12c46
--- /dev/null
+++ b/.changeset/calm-toes-melt.md
@@ -0,0 +1,5 @@
+---
+'@backstage/core-app-api': patch
+---
+
+The `defaultConfigLoader` now also reads configuration from scripts tags with `type="backstage.io/config"`. The tag is expected to contain a JSON-serialized array of `AppConfig` objects. If any of these script tags are present, the injected runtime configuration in the static assets will no longer be used.
diff --git a/packages/core-app-api/src/app/defaultConfigLoader.test.ts b/packages/core-app-api/src/app/defaultConfigLoader.test.tsx
similarity index 67%
rename from packages/core-app-api/src/app/defaultConfigLoader.test.ts
rename to packages/core-app-api/src/app/defaultConfigLoader.test.tsx
index c70ec3fbff..44d93aa625 100644
--- a/packages/core-app-api/src/app/defaultConfigLoader.test.ts
+++ b/packages/core-app-api/src/app/defaultConfigLoader.test.tsx
@@ -14,7 +14,10 @@
  * limitations under the License.
  */
 
+import React from 'react';
+import { render } from '@testing-library/react';
 import { defaultConfigLoaderSync } from './defaultConfigLoader';
+import { ConfigReader } from '@backstage/config';
 
 (process as any).env = { NODE_ENV: 'test' };
 const anyEnv = process.env as any;
@@ -53,6 +56,45 @@ describe('defaultConfigLoaderSync', () => {
     ]);
   });
 
+  it('loads config from script tags and ignore static config', () => {
+    anyEnv.APP_CONFIG = [];
+
+    render(
+      <script type="backstage.io/config">
+        {`[{"data":{"my":"config"},"context":"a"},{"data":{"my":"override-config"},"context":"b"}]`}
+      </script>,
+    );
+
+    const configs = (defaultConfigLoaderSync as any)('{"my":"runtime-config"}');
+    expect(configs).toEqual([
+      { data: { my: 'config' }, context: 'a' },
+      { data: { my: 'override-config' }, context: 'b' },
+    ]);
+    expect(ConfigReader.fromConfigs(configs).get('my')).toBe('override-config');
+  });
+
+  it('loads config from all script tags in order', () => {
+    anyEnv.APP_CONFIG = [];
+
+    render(
+      <>
+        <script type="backstage.io/config">
+          {`[{"data":{"my":"config"},"context":"a"}]`}
+        </script>
+        <script type="backstage.io/config">
+          {`[{"data":{"my":"override-config"},"context":"b"}]`}
+        </script>
+      </>,
+    );
+
+    const configs = (defaultConfigLoaderSync as any)('{"my":"runtime-config"}');
+    expect(configs).toEqual([
+      { data: { my: 'config' }, context: 'a' },
+      { data: { my: 'override-config' }, context: 'b' },
+    ]);
+    expect(ConfigReader.fromConfigs(configs).get('my')).toBe('override-config');
+  });
+
   it('fails to load invalid missing config', () => {
     expect(() => defaultConfigLoaderSync()).toThrow(
       'No static configuration provided',
diff --git a/packages/core-app-api/src/app/defaultConfigLoader.ts b/packages/core-app-api/src/app/defaultConfigLoader.ts
index 301b64a865..bfcef390ec 100644
--- a/packages/core-app-api/src/app/defaultConfigLoader.ts
+++ b/packages/core-app-api/src/app/defaultConfigLoader.ts
@@ -49,9 +49,36 @@ export function defaultConfigLoaderSync(
   }
   const configs = appConfig.slice() as unknown as AppConfig[];
 
-  // Avoiding this string also being replaced at runtime
-  if (
+  // Check if we have any config script tags, otherwise fall back to injected config
+  const configScripts = document.querySelectorAll(
+    'script[type="backstage.io/config"]',
+  );
+  if (configScripts.length > 0) {
+    for (const el of configScripts) {
+      try {
+        const content = el.textContent;
+        if (!content) {
+          throw new Error('tag is empty');
+        }
+        let data;
+        try {
+          data = JSON.parse(content);
+        } catch (error) {
+          throw new Error(`failed to parse config; ${error}`);
+        }
+        if (!Array.isArray(data)) {
+          throw new Error('data is not an array');
+        }
+        configs.push(...data);
+      } catch (error) {
+        throw new Error(
+          `Failed to load config from script tag, ${error.message}`,
+        );
+      }
+    }
+  } else if (
     runtimeConfigJson !==
+    // Avoiding this string also being replaced at runtime
     '__app_injected_runtime_config__'.toLocaleUpperCase('en-US')
   ) {
     try {