diff --git a/.changeset/giant-pots-dream.md b/.changeset/giant-pots-dream.md
new file mode 100644
index 0000000000..2baeb866a2
--- /dev/null
+++ b/.changeset/giant-pots-dream.md
@@ -0,0 +1,9 @@
+---
+'@techdocs/cli': patch
+'@backstage/create-app': patch
+'@backstage/repo-tools': patch
+'@backstage/codemods': patch
+'@backstage/cli': patch
+---
+
+Removed the `ts-node` dev dependency.
diff --git a/.github/workflows/sync_snyk-github-issues.yml b/.github/workflows/sync_snyk-github-issues.yml
index 638f5213be..149fc32958 100644
--- a/.github/workflows/sync_snyk-github-issues.yml
+++ b/.github/workflows/sync_snyk-github-issues.yml
@@ -43,6 +43,6 @@ jobs:
           SNYK_TOKEN: ${{ secrets.SNYK_TOKEN }}
           NODE_OPTIONS: --max-old-space-size=7168
       - name: Update Github issues
-        run: yarn ts-node scripts/snyk-github-issue-sync.ts
+        run: ./scripts/snyk-github-issue-sync.ts
         env:
           GITHUB_TOKEN: ${{ secrets.GITHUB_TOKEN }}
diff --git a/package.json b/package.json
index 98ec78baab..ed8f5cdedc 100644
--- a/package.json
+++ b/package.json
@@ -128,7 +128,6 @@
     "shx": "^0.3.2",
     "sloc": "^0.3.1",
     "sort-package-json": "^2.8.0",
-    "ts-node": "^10.4.0",
     "typescript": "~5.1.0"
   },
   "packageManager": "yarn@3.2.3",
diff --git a/packages/cli/bin/backstage-cli b/packages/cli/bin/backstage-cli
index 9aa82f6c2a..b721c8d3c1 100755
--- a/packages/cli/bin/backstage-cli
+++ b/packages/cli/bin/backstage-cli
@@ -24,14 +24,6 @@ const isLocal = require('fs').existsSync(path.resolve(__dirname, '../src'));
 if (!isLocal || process.env.BACKSTAGE_E2E_CLI_TEST) {
   require('..');
 } else {
-  require('ts-node').register({
-    transpileOnly: true,
-    /* eslint-disable-next-line no-restricted-syntax */
-    project: path.resolve(__dirname, '../../../tsconfig.json'),
-    compilerOptions: {
-      module: 'CommonJS',
-    },
-  });
-
+  require('@backstage/cli/config/nodeTransform.cjs');
   require('../src');
 }
diff --git a/packages/cli/knip-report.md b/packages/cli/knip-report.md
index 84e38cc861..16926bb87d 100644
--- a/packages/cli/knip-report.md
+++ b/packages/cli/knip-report.md
@@ -33,7 +33,7 @@
 | glob                             | package.json | error    |
 | util                             | package.json | error    |
 
-## Unused devDependencies (12)
+## Unused devDependencies (11)
 
 | Name                                    | Location     | Severity |
 | :-------------------------------------- | :----------- | :------- |
@@ -47,7 +47,6 @@
 | @types/svgo                             | package.json | error    |
 | @types/ejs                              | package.json | error    |
 | nodemon                                 | package.json | error    |
-| ts-node                                 | package.json | error    |
 | del                                     | package.json | error    |
 
 ## Referenced optional peerDependencies (4)
diff --git a/packages/cli/package.json b/packages/cli/package.json
index f633d1f607..f1214e3320 100644
--- a/packages/cli/package.json
+++ b/packages/cli/package.json
@@ -170,8 +170,7 @@
     "@types/yarnpkg__lockfile": "^1.1.4",
     "del": "^7.0.0",
     "msw": "^1.0.0",
-    "nodemon": "^3.0.1",
-    "ts-node": "^10.0.0"
+    "nodemon": "^3.0.1"
   },
   "peerDependencies": {
     "@vitejs/plugin-react": "^4.0.4",
diff --git a/packages/codemods/bin/backstage-codemods b/packages/codemods/bin/backstage-codemods
index 0bc4088cae..a43ae6324b 100755
--- a/packages/codemods/bin/backstage-codemods
+++ b/packages/codemods/bin/backstage-codemods
@@ -24,14 +24,6 @@ const isLocal = require('fs').existsSync(path.resolve(__dirname, '../src'));
 if (!isLocal) {
   require('..');
 } else {
-  require('ts-node').register({
-    transpileOnly: true,
-    /* eslint-disable-next-line no-restricted-syntax */
-    project: path.resolve(__dirname, '../../../tsconfig.json'),
-    compilerOptions: {
-      module: 'CommonJS',
-    },
-  });
-
+  require('@backstage/cli/config/nodeTransform.cjs');
   require('../src');
 }
diff --git a/packages/codemods/knip-report.md b/packages/codemods/knip-report.md
index f9903638ea..2661c35327 100644
--- a/packages/codemods/knip-report.md
+++ b/packages/codemods/knip-report.md
@@ -1,8 +1,2 @@
 # Knip report
 
-## Unused devDependencies (1)
-
-| Name    | Location     | Severity |
-| :------ | :----------- | :------- |
-| ts-node | package.json | error    |
-
diff --git a/packages/codemods/package.json b/packages/codemods/package.json
index 3fc1d63eae..202006d4c2 100644
--- a/packages/codemods/package.json
+++ b/packages/codemods/package.json
@@ -52,7 +52,6 @@
   "devDependencies": {
     "@backstage/cli": "workspace:^",
     "@types/jscodeshift": "^0.11.0",
-    "@types/node": "^18.17.8",
-    "ts-node": "^10.0.0"
+    "@types/node": "^18.17.8"
   }
 }
diff --git a/packages/create-app/bin/backstage-create-app b/packages/create-app/bin/backstage-create-app
index 4639ea96dc..bacee3e835 100755
--- a/packages/create-app/bin/backstage-create-app
+++ b/packages/create-app/bin/backstage-create-app
@@ -24,15 +24,6 @@ const isLocal = require('fs').existsSync(path.resolve(__dirname, '../src'));
 if (!isLocal || process.env.BACKSTAGE_E2E_CLI_TEST) {
   require('..');
 } else {
-  // Only used for development, so should be a devDependency
-  // eslint-disable-next-line @backstage/no-undeclared-imports
-  require('ts-node').register({
-    transpileOnly: true,
-    project: path.resolve(__dirname, '../../../tsconfig.json'),
-    compilerOptions: {
-      module: 'CommonJS',
-    },
-  });
-
+  require('@backstage/cli/config/nodeTransform.cjs');
   require('../src');
 }
diff --git a/packages/create-app/knip-report.md b/packages/create-app/knip-report.md
index dac197211b..65ef020fc3 100644
--- a/packages/create-app/knip-report.md
+++ b/packages/create-app/knip-report.md
@@ -1,10 +1,9 @@
 # Knip report
 
-## Unused devDependencies (3)
+## Unused devDependencies (2)
 
 | Name                  | Location     | Severity |
 | :-------------------- | :----------- | :------- |
 | @types/command-exists | package.json | error    |
 | nodemon               | package.json | error    |
-| ts-node               | package.json | error    |
 
diff --git a/packages/create-app/package.json b/packages/create-app/package.json
index 6f91013809..a0836ef09e 100644
--- a/packages/create-app/package.json
+++ b/packages/create-app/package.json
@@ -52,8 +52,7 @@
     "@types/node": "^18.17.8",
     "@types/recursive-readdir": "^2.2.0",
     "msw": "^1.0.0",
-    "nodemon": "^3.0.1",
-    "ts-node": "^10.0.0"
+    "nodemon": "^3.0.1"
   },
   "nodemonConfig": {
     "watch": "./src",
diff --git a/packages/e2e-test/bin/e2e-test b/packages/e2e-test/bin/e2e-test
index 27ed3472d5..495f72980b 100755
--- a/packages/e2e-test/bin/e2e-test
+++ b/packages/e2e-test/bin/e2e-test
@@ -15,15 +15,5 @@
  * limitations under the License.
  */
 
-const path = require('path');
-
-require('ts-node').register({
-  transpileOnly: true,
-  /* eslint-disable-next-line no-restricted-syntax */
-  project: path.resolve(__dirname, '../../../tsconfig.json'),
-  compilerOptions: {
-    module: 'CommonJS',
-  },
-});
-
+require('@backstage/cli/config/nodeTransform.cjs');
 require('../src');
diff --git a/packages/e2e-test/knip-report.md b/packages/e2e-test/knip-report.md
index 4020464e7b..baf9661c0a 100644
--- a/packages/e2e-test/knip-report.md
+++ b/packages/e2e-test/knip-report.md
@@ -1,10 +1,9 @@
 # Knip report
 
-## Unused devDependencies (3)
+## Unused devDependencies (2)
 
 | Name             | Location     | Severity |
 | :--------------- | :----------- | :------- |
 | @types/puppeteer | package.json | error    |
 | nodemon          | package.json | error    |
-| ts-node          | package.json | error    |
 
diff --git a/packages/e2e-test/package.json b/packages/e2e-test/package.json
index 0bd2d8ec76..00cde5e2ab 100644
--- a/packages/e2e-test/package.json
+++ b/packages/e2e-test/package.json
@@ -44,8 +44,7 @@
     "@types/fs-extra": "^11.0.0",
     "@types/node": "^18.17.8",
     "@types/puppeteer": "^5.4.4",
-    "nodemon": "^3.0.1",
-    "ts-node": "^10.0.0"
+    "nodemon": "^3.0.1"
   },
   "nodemonConfig": {
     "watch": "./src",
diff --git a/packages/repo-tools/bin/backstage-repo-tools b/packages/repo-tools/bin/backstage-repo-tools
index 377e4a32ca..b723d215fd 100755
--- a/packages/repo-tools/bin/backstage-repo-tools
+++ b/packages/repo-tools/bin/backstage-repo-tools
@@ -24,14 +24,6 @@ const isLocal = require('fs').existsSync(path.resolve(__dirname, '../src'));
 if (!isLocal || process.env.BACKSTAGE_E2E_CLI_TEST) {
   require('..');
 } else {
-  require('ts-node').register({
-    transpileOnly: true,
-    /* eslint-disable-next-line no-restricted-syntax */
-    project: path.resolve(__dirname, '../../../tsconfig.json'),
-    compilerOptions: {
-      module: 'CommonJS',
-    },
-  });
-
+  require('@backstage/cli/config/nodeTransform.cjs');
   require('../src');
 }
diff --git a/packages/repo-tools/knip-report.md b/packages/repo-tools/knip-report.md
index 7571c6922d..32502b699c 100644
--- a/packages/repo-tools/knip-report.md
+++ b/packages/repo-tools/knip-report.md
@@ -1,6 +1,6 @@
 # Knip report
 
-## Unused dependencies (6)
+## Unused dependencies (5)
 
 | Name                                | Location     | Severity |
 | :---------------------------------- | :----------- | :------- |
@@ -8,7 +8,6 @@
 | @stoplight/spectral-functions       | package.json | error    |
 | @stoplight/spectral-runtime         | package.json | error    |
 | is-glob                             | package.json | error    |
-| ts-node                             | package.json | error    |
 | glob                                | package.json | error    |
 
 ## Unused devDependencies (1)
diff --git a/packages/repo-tools/package.json b/packages/repo-tools/package.json
index 73195e8816..6550c5840b 100644
--- a/packages/repo-tools/package.json
+++ b/packages/repo-tools/package.json
@@ -59,7 +59,6 @@
     "minimatch": "^9.0.0",
     "p-limit": "^3.0.2",
     "portfinder": "^1.0.32",
-    "ts-node": "^10.0.0",
     "yaml-diff-patch": "^2.0.0"
   },
   "devDependencies": {
diff --git a/packages/techdocs-cli/bin/techdocs-cli b/packages/techdocs-cli/bin/techdocs-cli
index 6c0bbd37b5..a43ae6324b 100755
--- a/packages/techdocs-cli/bin/techdocs-cli
+++ b/packages/techdocs-cli/bin/techdocs-cli
@@ -24,13 +24,6 @@ const isLocal = require('fs').existsSync(path.resolve(__dirname, '../src'));
 if (!isLocal) {
   require('..');
 } else {
-  require('ts-node').register({
-    transpileOnly: true,
-    project: path.resolve(__dirname, '../../../tsconfig.json'),
-    compilerOptions: {
-      module: 'CommonJS',
-    },
-  });
-
+  require('@backstage/cli/config/nodeTransform.cjs');
   require('../src');
 }
diff --git a/packages/techdocs-cli/knip-report.md b/packages/techdocs-cli/knip-report.md
index 06b1586f74..7329783857 100644
--- a/packages/techdocs-cli/knip-report.md
+++ b/packages/techdocs-cli/knip-report.md
@@ -6,11 +6,10 @@
 | :----------- | :----------- | :------- |
 | global-agent | package.json | error    |
 
-## Unused devDependencies (3)
+## Unused devDependencies (2)
 
 | Name               | Location     | Severity |
 | :----------------- | :----------- | :------- |
 | @types/webpack-env | package.json | error    |
 | nodemon            | package.json | error    |
-| ts-node            | package.json | error    |
 
diff --git a/packages/techdocs-cli/package.json b/packages/techdocs-cli/package.json
index ecda27819d..b1be4ac055 100644
--- a/packages/techdocs-cli/package.json
+++ b/packages/techdocs-cli/package.json
@@ -44,8 +44,7 @@
     "@types/webpack-env": "^1.15.3",
     "find-process": "^1.4.5",
     "nodemon": "^3.0.1",
-    "techdocs-cli-embedded-app": "link:../techdocs-cli-embedded-app",
-    "ts-node": "^10.0.0"
+    "techdocs-cli-embedded-app": "link:../techdocs-cli-embedded-app"
   },
   "files": [
     "bin",
diff --git a/scripts/snyk-github-issue-sync.ts b/scripts/snyk-github-issue-sync.ts
index ea7d42a2a4..21bb852b5f 100755
--- a/scripts/snyk-github-issue-sync.ts
+++ b/scripts/snyk-github-issue-sync.ts
@@ -1,4 +1,4 @@
-#!/usr/bin/env yarn ts-node --transpile-only
+#!/usr/bin/env node --require @backstage/cli/config/nodeTransform.cjs
 /*
  * Copyright 2021 The Backstage Authors
  *
diff --git a/yarn.lock b/yarn.lock
index d2b6b8b95b..2dda73ed3a 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -3710,7 +3710,6 @@ __metadata:
     swc-loader: ^0.2.3
     tar: ^6.1.12
     terser-webpack-plugin: ^5.1.3
-    ts-node: ^10.0.0
     util: ^0.12.3
     webpack: ^5.70.0
     webpack-dev-server: ^4.7.3
@@ -3750,7 +3749,6 @@ __metadata:
     commander: ^12.0.0
     jscodeshift: ^0.15.0
     jscodeshift-add-imports: ^1.0.10
-    ts-node: ^10.0.0
   bin:
     backstage-codemods: bin/backstage-codemods
   languageName: unknown
@@ -4106,7 +4104,6 @@ __metadata:
     nodemon: ^3.0.1
     ora: ^5.3.0
     recursive-readdir: ^2.2.2
-    ts-node: ^10.0.0
   bin:
     backstage-create-app: bin/backstage-create-app
   languageName: unknown
@@ -10138,7 +10135,6 @@ __metadata:
     minimatch: ^9.0.0
     p-limit: ^3.0.2
     portfinder: ^1.0.32
-    ts-node: ^10.0.0
     yaml-diff-patch: ^2.0.0
   peerDependencies:
     "@microsoft/api-extractor-model": "*"
@@ -17905,7 +17901,6 @@ __metadata:
     react-dev-utils: ^12.0.0-next.60
     serve-handler: ^6.1.3
     techdocs-cli-embedded-app: "link:../techdocs-cli-embedded-app"
-    ts-node: ^10.0.0
     winston: ^3.2.1
   bin:
     techdocs-cli: bin/techdocs-cli
@@ -26043,7 +26038,6 @@ __metadata:
     nodemon: ^3.0.1
     pgtools: ^1.0.0
     tree-kill: ^1.2.2
-    ts-node: ^10.0.0
   bin:
     e2e-test: bin/e2e-test
   languageName: unknown
@@ -41157,7 +41151,6 @@ __metadata:
     shx: ^0.3.2
     sloc: ^0.3.1
     sort-package-json: ^2.8.0
-    ts-node: ^10.4.0
     typescript: ~5.1.0
   languageName: unknown
   linkType: soft
@@ -43998,7 +43991,7 @@ __metadata:
   languageName: node
   linkType: hard
 
-"ts-node@npm:^10.0.0, ts-node@npm:^10.4.0, ts-node@npm:^10.9.1":
+"ts-node@npm:^10.9.1":
   version: 10.9.2
   resolution: "ts-node@npm:10.9.2"
   dependencies: